KROMISAN
(Chromium Supplement)

Chromium is an essential nutrient involved in the regulation of carbohydrate, lipid metabolism and energy generation in the cells. In KROMISAN chromium is found in the form of picolinate which is easily absorbed into tissue.

Description

• Registered food supplementation containing starch - soya protein - chromium picolinate preparation.
• Ingredients and additives:

       maize starch..........83,0%
       soy protein...........15,0%
       chromium picolinate....0,1%
       anti-clumping agent... E551
       binding agent.........E470b

• The daily dosage 1 tablet contains 50 µg chromium (Cr), which is equivalent to 100 % of daily need (RDA).
• Contains no lactose, yeast or sugars.
• Package:
  120 tablets / 48 g
  300 tablets / 120 g

Usage

• Chromium is an essential trace element involved in the metabolism of carbohydrates, lipids, and proteins mainly by increasing the efficiency of insulin. Chromium functions in maintaining normal glucose tolerance primarily by regulating insulin action.
• Chromium deficiency affects the maintenance of normal glucose tolerance and healthy lipid profiles. However, the dietary intake of chromium in humans is often suboptimal.
• Insufficient dietary chromium is associated with glucose intolerance which appear widespread in the general population.
• Improved chromium nutrition leads to improved sugar metabolism in hypoglycemics, hyperglycemics, and diabetics. Chromium has been found to lower the proportional amount of the harmful LDL-cholesterol in blood.
• Chromium has been reported to increase lean body mass and decrease percentage body fat, which may lead to weight loss in humans.

References

1. A double-blind, placebo-controlled, exploratory trial of chromium picolinate in atypical depression: effect on carbohydrate craving.
   Docherty JP, et al
   J Psychiatr Pract. 2005 Sep;11(5):302-14.
2. Effect of chromium supplementation on blood glucose and lipid levels in type 2 diabetes mellitus elderly patients.
   Rabinovitz H, Friedensohn A, Leibovitz A, Gabay G, Rocas C, Habot B.
   Int J Vitam Nutr Res. 2004 May;74(3):178-82.
3. A scientific review: the role of chromium in insulin resistance.
   Diabetes Educ. 2004;Suppl:2-14.
   [No authors listed]
4. Chromium picolinate for reducing body weight: meta-analysis of randomized trials.
   Pittler MH, Stevinson C, Ernst E.
   Int J Obes Relat Metab Disord. 2003 Apr;27(4):522-9.
5. The safety and efficacy of high-dose chromium.
   Lamson DS, Plaza SM.
   Altern Med Rev. 2002 Jun;7(3):218-35.
6. Chromium, exercise, and body composition.
   Kobla HV, Volpe SL
   Crit Rev Food Sci Nutr 2000 Jul;40(4):291-308
7. W. Mertz
   Chromium in human nutrition: a review
   J. Nutr.123, 626-633 (1993)
8. Anderson RA, Cheng N, Bryden NA, Polansky MM, Cheng N, Chi J, Feng J.
   Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes.
   Diabetes. 1997 Nov;46(11):1786-91.
9. R. A. Anderson et al.
   Lack of toxicity of chromium chloride and chromium picolinate in rats
   J. Am. Coll. Nutr. 16, 273-279 (1997)
10. R. A. Anderson
    Chromium, glucose tolerance, and diabetes
    Biol. Trace Elem. Res. 32, 19-24 (1992)
11. R. A. Anderson
    Recent advances in the clinical and biochemical effects of chromium deficiency
    Prog. Clin. Biol. Res. 380, 221-234 (1993)
12. R. A. Anderson et al.
    Supplemental-chromium effects on glucose, insulin, glucagon, and urinary chromium losses in subjects consuming controlled low-chromium diets
    Am.J. Clin. Nutr. 54, 909-916 (1991)
13. R.A.Anderson
    Effects of chromium on body composition and weight loss.
    Nutr. Rev. 56, 9, 266-70 (1998)

    (References searched and cited from National Library of Medicine-PubMed at http://www.ncbi.nlm.nih.gov/PubMed/ )

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    Updated August 18, 2006